The EFFECT-Dep study: Enhancing the effectiveness of electroconvulsive therapy in severe depressio

Not Applicable

Completed

• Conditions: Major depression; Mental and Behavioural Disorders; Depressive episode

• Registration Number: ISRCTN23577151
• Lead Sponsor: St Patrick's Hospital (Ireland)

Brief Summary

1. 2016 results in http://www.ncbi.nlm.nih.gov/pubmed/26892939 2. 2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/30365982 3. 2021 results in https://pubmed.ncbi.nlm.nih.gov/33586144/ (added 16/02/2021) 4. 2021 results in https://pubmed.ncbi.nlm.nih.gov/34033117/ (added 26/05/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-06-27
• Study Completion: 2014-10-31
• Last Update Posted: 7 June 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

Participants in the trial will be patients greater than or equal to 18 years (either sex) with major depressive disorder (Diagnostic and Statistical Manual of Mental Disorders, fourth edition [DSM-IV]) and referred for ECT.

Exclusion Criteria

1. Any condition rendering patients medically unfit for general anaesthesia or ECT
2. Treatment with ECT in previous six months
3. Dementia or other axis 1 diagnosis
4. Alcohol/other substance abuse in previous six months
5. Inability/refusal to consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified