FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma

• Conditions: Acute Bronchiolitis

• Registration Number: NCT02093715
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-07
• Study First Submitted: 2014-03-19
• Study First Submitted QC: 2014-03-20
• Study First Posted: 2014-03-21
• Status Verified: 2014-06
• Last Update Submitted: 2014-08-31
• Last Update Posted: 2014-09-03
• Primary Completion: 2020-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• First episode of shortness of breath
• Children in ages 2 weeks to 2 years

Exclusion Criteria

• Any chronic disease
• Congenital anomalies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Physician diagnosed asthma	At the age of 4 years	Modification of The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires

Secondary Outcome Measures

Name	Time	Method
Fractional exhaled Nitric Oxide (FENO) level	During acute bronchiolitis, after 2 and 6 months	FeNO level measured by a rapid-response chemiluminescence analyzer (Eco Physics CLD88 NO analyzer, EcoMedics AG,Switzerland).

Trial Locations

Locations (1)

Sourasky Medical Center; 🇮🇱 Tel-Aviv, Israel