Fractional exhaled nitric oxide (FeNO) in airway involvement by relapsing polychondritis (RP)
Not Applicable
- Conditions
- patients with relapsing polychondritis patients with bronchial asthma healthy volunteers
- Registration Number
- JPRN-UMIN000007829
- Lead Sponsor
- St. Marianna University School of Medicine Division of Respiratory and Infectious Diseases, Department of Internal Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
1) Refused informed consent 2) Exacerbation within the last 3 months for bronchial asthma 3) Patients who are pregnant, possibly pregnant, or lactating. 4) Patients with renal failure. (serum creatinine > 2.0 mg/dL, BUN > 30mg/dl) 5) AST or ALT > 100IU 6) Patients with severe diabetes, hyperlipidemia or hyperuricemia 7) Patients who are judged inappropriate by the investigator in charge.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare FeNO between patients with relapsing polychondritis and healthy volunteers, and patients with relapsing polychondritis and bronchial asthma
- Secondary Outcome Measures
Name Time Method 1. Correlation between FeNO2 and subject complaints (mMRC, Borg scale and VAS) 2. Correlation between FeNO and pulmonary function tests (spirometry and IOS) 3. Correlation between FeNO and eosinophil in sputum 4. Correlation between FeNO and CRP, ESR and MMP-3 5. Variation coefficient of FeNO