Fractional concentration of nitric oxide in exhaled breath in children aged 7-10: survey in a primary health care setting

Completed

• Conditions: Asthma; asthma symptoms; 10006436

• Registration Number: NL-OMON33345
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 450

Inclusion Criteria

alle children aged 7-10 years

Exclusion Criteria

Children with a doctor*s diagnosis of asthma and asthma medication in the past twelve months.
Children with a contra-indication for salbutamol.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters are the ISAAC questionnaire for asthma, rhinitis and<br /><br>eczema, spirometry (FEV1 and FVC), airway reversibility testing with salbutamol<br /><br>and FENO. Sensitivity, specificity, positive predictive value (PPV) and<br /><br>negative predictive value (NPV) of FENO and airway reversibility in undiagnosed<br /><br>asthma in children aged 7-10 years will be analysed.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>