NCT00767208已完成不适用
Comparison of Postprandial Metabolic Responses Between Type 2 Diabetic and Healthy Overweight Subjects
Centre de Recherche en Nutrition Humaine Rhone-Alpe2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2005年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Apparition of exogenous glucose in plasma in the postprandial phase and its effect on carbohydrate and lipid metabolism
研究概览
简要总结
The aim of this trial was to compare postprandial metabolic response to glucose load in healthy overweight and type 2 diabetic subjects, by using glycemia, insulinemia, lipid profile, nutrient oxidation follow-up. Stable isotopes of glucose were used to assess postprandial total,exogenous and endogenous glucose kinetics.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Overweight or obese volunteers
- •Healthy for one group nd type 2 diabetic for the second group
- •Age between 30 and 65 years old
- •Total cholesterol < or = 7 mmol/l and triglycerides < or = 4 mmol/l
- •For diabetic group: treated by metformin and/or sulfonylurea and/or thiazolidinedione and HbA1c < 6%
- •Stable weight over last 3 months
- •Informed consent
排除标准
- •No compliant subjects
- •Participation in an other trial 2 months before starting this one
- •Ward of court or under guardianship (sheltered adults)
- •Person deprived of freedom by judicial or administrative decision
- •Type 1 diabetes and type 2 diabetes treated bu insulin or acarbose
- •Existence of a previously diagnosed pathology (other than type 2 diabetes)
- •Previous gastro-intestinal pathology
- •Treated by corticoids, anorexigens, weight loss medicines
- •Alcoholism or severe tobacco consumption
结局指标
主要结局
Apparition of exogenous glucose in plasma in the postprandial phase and its effect on carbohydrate and lipid metabolism
时间窗: 6 hours postprandially
次要结局
- Postprandial concentrations of glucose, non esterified fatty acids, insulin and triglycerides(6 hours postprandially)
- Carbohydrate and lipid oxidation(6 hours postprandially)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
A Clinical Study to Investigate and Compare the Impact of High Protein Pasta, Lower Protein Pasta and White Rice on Blood Sugar Control in People With Type 1 Diabetes Mellitus (T1DM)Diabetes Mellitus, Type 1NCT03362151Sansum Diabetes Research Institute14
已完成
不适用
Monitoring Postprandial Glycemia in Fruit SnacksBlood GlucoseNCT05961475Ocean Spray Cranberries, Inc.20
已完成
不适用
Glycemic Response in Adults With Type 2 DiabetesGlycemic ControlNCT05166200Abbott Nutrition26
已完成
不适用
Postprandial Glycemic Response in Adults With Type 2 DiabetesGlycemic ControlNCT05154045Abbott Nutrition26
已完成
不适用
Monitoring Postprandial Blood Glucose and Insulin in Fruit SnacksBlood GlucoseBlood InsulinNCT06458946Ocean Spray Cranberries, Inc.24