Vestibular function in the follow-up of patients with Vestibular Schwannoma (FUVES)

Recruiting

Conditions: vestibular function
vestibular schwannoma - acoustic neuroma
10022396

Registration Number: NL-OMON52093

Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 65

Inclusion Criteria

• aged 18 years or older
• being diagnosed with unilateral vestibular schwannoma
• with or without active VS treatment indication (i.e. RT, S or AS)
• with or without severe vestibular signs or symptoms
• able to provide a written informed consent

Exclusion Criteria

• active additional neuro- otologic disorders
• severe disability (e.g. neurological, cardiovascular, orthopedic,
psychiatric) or
• serious concurrent illness that might interfere with vestibular evaluation
• patients under medical treatment that affects the vestibular function

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The changes in objective vestibular test results and dizziness related QoL<br /><br>during follow-up. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• To correlate the pre-operative vestibular function with the post-operative<br /><br>patient vestibular disability and handicap.<br /><br>• To correlate the irradiation dose-volume to the vestibular organs with<br /><br>vestibulo-toxicity after radiotherapy.<br /><br>• To correlate the natural development of the vestibular function over time in<br /><br>active surveillance.<br /><br>• To determine the effect of ITG in the vestibular function and vestibular<br /><br>complaints, with objective and subjective vestibular tests.<br /><br>• To correlate the questionnaires (DHI, PANQOL and SF-36) results with<br /><br>vestibular function.</p><br>