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Clinical Trials/NCT02806934
NCT02806934CompletedNot Applicable

Tumor Necrosis Factor-308 Polymorphism a Embryo Implantation Rate in Women Undergoing in Vitro Fertilization

Centre Hospitalier Universitaire de Nice1 site in 1 country120 target enrollmentStarted: June 2009Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
120
Locations
1
Primary Endpoint
Implantation rate by ultrasound test

Study Overview

Brief Summary

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

Detailed Description

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 37 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • normal karyotype,
  • age under 38 years
  • serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l

Exclusion Criteria

  • age under 18 years

Outcomes

Primary Outcomes

Implantation rate by ultrasound test

Time Frame: 20 days after implantation

Implantation rate by biological test

Time Frame: 20 days after implantation

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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