The effect of a low FODMAP diet on luminal microbiota, fermentation and symptoms: A randomised controlled trial

King's College London (UK)0 个研究点目标入组 40 人开始时间: 2010年3月8日最近更新: 2015年1月13日

适应症

试验速览

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•Patients will be recruited from Gastrointestinal and Dietetic Outpatient clinics at Guy?s and St Thomas? NHS Foundation Trust, London, UK.
•1. Adult patients aged 18-65 years
•2. Identified as having IBS based on Rome III criteria
•3. Symptoms including bloating and/or diarrhoea

•1. Patients with any other gastrointestinal disease or gastrointestinal surgery
•2. Patients whose major IBS symptom is constipation
•3. Patients receiving lactulose or any other probiotic or prebiotic substances in the four weeks prior to the study
•4. Patients who have taken antibiotics in the 4 weeks prior to the study
•5. Patients who have received bowel preparation for investigative procedures in the 4 weeks prior to the study
•6. Patients with any other significant major organ disorders, including diabetes, psychiatric and current eating disorders
•7. Patients who report to be pregnant or lactating
•8. Patients who have had changes to IBS medications or dose in the 4 weeks prior to the study

发起方

King's College London (UK)