utritional support in cirrhotic patients with hepatocellular carcinoma
- Conditions
- iver cirrhosis with hepatocellular carcinoma
- Registration Number
- JPRN-UMIN000004158
- Lead Sponsor
- The first department of internal medicine,Yamaguchi University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 125
Not provided
1)Patients with sensitivities for BCAA-enriched mixture. 2)Patients with sensitivities for alfa-glucosidase inhibitor. 3)Diabetic patients who are used oral antidiabetic agent or insulin. 4)Diabetic patients who had severe diadetic ketosis, diadetic coma, or precoma stage. 5)Decompensated liver cirrhostic patients who were difficult to treat(for example, total bilirubin, over 3.0mg/dl; hepatic coma, coma grade over grade II; treatment-resistant ascites). 6)Patients who had serum albumin, <2.5g/dl 7)Patients who had severe renal failure(i.e. serum creatinine, over 2mg/dl) 8)Patients who had severe hernia, stenosis of colon or inflammation of colon. 9)Patients who were difficult to take sufficient diet(i.e.protein control). 10)Patients who had congenital amino-acid metabolism abnormality. 11)Patients who had milk allergy. 12)Patients who were disqualified by doctor in attendance.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in insulin resistance
- Secondary Outcome Measures
Name Time Method 1) Evaluation for nutritional status 2) Incidence of complicating disease 3) Prognosis