NCT04600193Unknown不适用
a Randomized Controlled Trial of the Intake of Organic and Inorganic Phosphate in Peritoneal Dialysis Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Plasma levels of phosphate
研究概览
简要总结
Hyperphosphatemia is a common problem among patientens suffering from chronic kidney disease. Hyperphosphatemia is associated with increased risk of cardiovascular diseases. One of the treatments are through the diet, where patients are instructed ind reducing their daily intake of phosphate. But since phosphate exists in both organic and inorganic forms in the diet, this leads to several problems. Informations of the bioavability and furthermore the effect of plasma koncentrations of phosphate are lacking for both forms of phosphate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients > 18 years
- •Competent
- •The patient should be able to take a sample of p-fluid and urine by himself
- •Chronic peritoneal dialysis
- •Reads and understand danish
- •Has been informed written and oraly about the study and signed informed consent
- •P-phosphate koncentrations 0,7-2,0 .mol/l
- •P - ioniset calcium 1,1-1,4 mmol/l
排除标准
- •Pregnant or breast-feeding
- •Terminal patients
- •If the experience acute infections or other acute situations they will be excluded from the study
结局指标
主要结局
Plasma levels of phosphate
时间窗: six days
次要结局
- Changes in p-sodium(six days)
- Changes in p-magnesium(six days)
- changes in p-calcium(six days)
- Koncentration of phosphate in peritoneal dialysis fluid(six days)
- Changes in p-phosphate(six days)
- changes in p-PTH(six days)
- Changes in p-potassium(six days)
- Changes in p-FGF23(six days)
- Koncentration of phosphate in urine(six days)
研究者
Jens Rikardt Andersen
Associate professor at the university of Copenhagen
University of Copenhagen
研究点 (2)
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