A Randomized Controlled Trial to Evaluate the Efficacy of Reducing High-Phosphate Containing Diet Education and Proper Phosphate Binder Intake Education to Serum Phosphate Level Among Maintenance Hemodialysis Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 主要终点
- The proportion of patients who reached Ca x P product lower than 55
研究概览
简要总结
Hyperphosphatemia is an independent risk factor for mortality among dialysis patients. And most phosphate in human is derived from the food. The purpose of this study is to evaluate the efficacy of nutritional consultation and education on phosphate binder among dialysis patients.
详细描述
Hyperphosphatemia is an independent risk factor for mortality among dialysis patients. Hyperphosphatemia is associated with increased incidence of cardiovascular diseases, and is a mediator to the development of hyperparathyroidism and mineral bone disorder. Phosphate is usually obtained by food intake, and it can be removed by hemodialysis. However, the efficacy of removal is limited, so that dietary education and proper intake of phosphate binder is essential.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •End-stage renal disease patients whose dialysis vintage is more than 3 months
排除标准
- •Patients with liver cirrhosis
- •Pregnant patients
- •Patients with alimentary tract malabsorption diseases
- •History of recent alcohol or drug abuse
- •Patients receiving chemotherapy for solid organ tumor
- •History of mental illness (major depressive disorder, bipolar disorder, schizophrenia, etc.)
- •Patients having difficulty communicating with our medical team (dementia, mental retardation, etc.)
结局指标
主要结局
The proportion of patients who reached Ca x P product lower than 55
时间窗: 2-3 month
次要结局
- Changes of bioequivalent dose of phosphate binder(2-3 month)
- Changes of MMAS-8 score(1 month, 2-3 month)
- Amount of change in dietary phosphorus intake(2-3 month)
- Changes of PG-SGA(2-3 month)
研究者
Jong Cheol Jeong
Clinical Assistant Professor
Ajou University School of Medicine