TCTR20220630001
Unknown
Not Applicable
Gut microbiota and its metabolite changes in post-myocardial infarction patients
The faculty of Medicine endowment fund0 sites120 target enrollmentJune 30, 2022
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute coronary syndrome
- Sponsor
- The faculty of Medicine endowment fund
- Enrollment
- 120
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Post ACS group
- •1\. Age 18 to 80 years old
- •2\. Diagnosed of acute coronary syndrome (ST\-elevation myocardial infarction or non\-ST\-elevation myocardial infarction) patients receiving coronary angiography or revacularization within 12 to 24 hours at Cardiovascular and Critical Care unit in Maharaj Nakorn Chiang Mai hospital
- •Normal population group
- •1\. Age 18 to 80 years old
- •2\. Healthy volunteer who has age sex and comorbidities matched at Outpatients clinic of Internal medicine department at Maharaj Nakorn Chiang Mai hospital
- •2\.1 Hypertension defined as
- •home BP more than 135 over 85
- •or on antihypertensive medication
- •2\.2 Diabetes mellitus type 2 defined as HbA1c more than 7 percent or less than 7 percent
Exclusion Criteria
- •1\. Cardiac arrest and cannot be recover
- •2\. Life expectancy less than 1 year
- •3\. History of acute cardiovascular events (including acute coronary syndrome, stroke, heart failure, acute/critical limb ischemia)
- •4\. History of heart failure reduced ejection fraction
- •5\. History of antibiotics or probiotics in past 4 weeks before recruitment
- •6\. Active infection within 1 week
- •7\. Severe valvular heart disease
- •8\. Informed consent refusal
Outcomes
Primary Outcomes
Not specified
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