RP3 biomarker levels before and after endodontic treatment in symptomatic apical periodontitis
Phase 4
- Conditions
- Health Condition 1: K044- Acute apical periodontitis of pulpal origin
- Registration Number
- CTRI/2024/05/066690
- Lead Sponsor
- Karina
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients diagnosed with pulp necrosis and symptomatic apical periodontitis in a single tooth as per the clinical and pulp sensibility tests (according to the AAE guidelines)
2. Patients aged 18-40 years of age
3. Patients with no relevant medical history or absence of any systemic conditions
4. Non-smokers
Exclusion Criteria
1. Patients with periodontitis
2.Patients with multiple carious teeth
3. Patients with apical abscess (swelling) &/or sinus tract
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The NLRP3 levels in GCF may be increased and hence detectable in patients with Pulp Necrosis and Symptomatic Apical Periodontitis but will reduce after endodontic treatmentTimepoint: One week after completion of endodontic treatment.
- Secondary Outcome Measures
Name Time Method /ATimepoint: N/A