Periodontal Status And Gingival Crevicular Fluid Sclerostin, IL-1ß and MMP-8 Levels in Ankylosing Spondylitis

Not Applicable

Completed

• Conditions: Ankylosing Spondylitis; ankylosing spondylitis; sclerostin; cytokine; periodontal disease; gingival crevicular fluid; periodontal parameter

• Registration Number: TCTR20200908001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-08-28
• Study Start: 2020-09-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

All patients with AS had been diagnosed according to the criteria of the Modified New York Criteria.

Exclusion Criteria

The exclusion criteria for AS group is; other systemic diseases in addition to AS (chronic heart diseases, diabetes mellitus, endocarditis), pregnancy or lactation, infectious diseases (hepatitis, HIV/AIDS, tuberculosis) and limited mobility. Exclusion criteria for both groups are current smokers, history of periodontal therapy during the last 6 months, and use of antibiotics at least 6 months before the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
sclerostin levels at periodontal examinaton pg/30sec,ınterleukin-1beta levels at periodontal examinaton pg/30sec,MMP-8 levels at periodontal examinaton pg/30sec

Secondary Outcome Measures

Name	Time	Method
one None None