跳至主要内容
临床试验/ACTRN12622000182796
ACTRN12622000182796进行中(未招募)未知

The feasibility of a personalized approach to venous thromboembolism prophylaxis in heavier critically ill patients.

Royal Melbourne Hospital0 个研究点目标入组 53 人开始时间: 2022年2月2日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
入组人数
53

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Prevention
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • I. Adult patients greater than or equal to 18 years of age
  • II. Admitted to RMH ICU
  • III. Admission weight recorded as greater than or equal to 100 kg
  • IV. Suitable to receive VTE chemoprophylaxis with enoxaparin (a Low Weight Molecular Heparin)

排除标准

  • I. Renal impairment that would cause a reduction in chemoprophylaxis dosing (eGFR < 30 ml/min).
  • II. Admitted after cardiac- neuro- or spinal surgery
  • III. Pregnancy
  • IV. Abnormal baseline coagulation (INR >1.5 or APTT >60 sec or platelets <50 × 109/L)
  • V. Require therapeutic anti-coagulation
  • VI. Treating intensivist believes either a fixed dose (40mg BD) OR weight-based dynamic adjustment dosing regimen is required for that patient.
  • VII. Received > 3 doses of enoxaparin in this ICU admission

研究者

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