Assessment of suitable Antihypertensive therapies: Combination with high dose amlodipine/Irbesartan vs. triple combination with amlodipine/Irbesartan/Indapamide - ASAHI-AI study

Asahikawa Medical University0 个研究点目标入组 94 人开始时间: 2014年3月6日最近更新: 2023年10月17日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方: Asahikawa Medical University
入组人数: 94

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

High-dose CCBs combined with ARBs and a triple combination with diuretics combined with standard-dose CCB/ARBs produced a similar efficacy in reducing the BP. Both combination therapies can be used safely and effectively in hypertensive patients uncontrolled by standard doses of ARBs and CCBs.

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 85years-old（—）
性别: All

入选标准

未提供

排除标准

•1) Patients with secondary hypertension 2) Patients with a history of severe renal disease: serum creatinine>2.0 mg/dl 3) Patients with critical liver damage (AST or ALT>100 IU/l) 4) Patients with a history of adverse effects to ARBs 5) Bilateral renal artery stenosis 6) Patients with hyperkalemia >=5.5 mEq/L 7) Patients with pregnancy or breast-feeding 8) Patients with a poor prognosis such as a malignant tumor 9) Patients who are considered not to be eligible for the study by the investigator due to medical reasons

研究者

发起方

Asahikawa Medical University

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