Characterisation of Occupational Allergy to Drosophila
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Number of participants with positive prick test to drosophila
研究概览
简要总结
Allergy is a very common problem and can be a handicap in everyday life, specially when symptoms occur at work place. Some persons working with drosophila developed respiratory symptoms. Investigators tried to analyze if these manifestations could be due to a specific allergy to drosophila.
详细描述
To do so, investigators invited laboratory workers who presented any symptoms in presence of drosophila to undergo skin prick tests in order to determine if a specific sensibilization to drosophila exists. Then, a blood sample is taken from these persons to research specific IgE directed against drosophila. By this way, investigators hope determine if a specific allergy to drosophila exists, its characteristics as prevalence, symptoms, populations concerned...in order to better protect laboratory workers and prevent allergy incidence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 68 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •major males or females (aged <68) who work in laboratory with drosophila in Montpellier (France)
- •clinical symptoms in presence of drosophila
- •The subject must be affiliated to a social security scheme
- •Provision of informed consent prior to any study specific procedures
排除标准
- •The patient has indicated against (or incompatible drug combination) concerning the implementation of a prick test
- •antihistamine cure in progress
- •Inability to understand the nature and goals of the study and / or communication difficulties with the investigator
- •No affiliation to a French social security recipient or not such a scheme
- •Major protected by law (guardianship, curator or under judicial protection)
- •deprivation of liberty by judicial or administrative decision
- •Increased likelihood of non compliance to the protocol or abandonment under study
- •pregnancy or breastfeeding
研究组 & 干预措施
laboratory workers with symptoms in presence of drosophila
干预措施: blood test (four dry tubes 7ml) and prick tests (Other)
结局指标
主要结局
Number of participants with positive prick test to drosophila
时间窗: The day of inclusion
Prick tests : measuring the size of the skin reaction (wheal) after prick tests with drosophila. A wheal measuring more than 4 millimeters in diameter sign a sensitization to drosophila. Then, a blood sample is collected in order to measure specific drosophila IgE rate
次要结局
- Survey to analyse risk factors for allergy to drosophila(The day of inclusion)