Study of Eye Movements as Markers of the Physiological, Cerebral and Cognitive State of Healthy Subjects
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- University Hospital, Grenoble
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Eye movement brain networks
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The goal of this study is the multimodal exploration via eyetracking, MRI and EEG data of ocular movements and the corresponding brain activation during ecologic visual stimulation in the healthy population.
Detailed Description
Cerebral activation following visual stimulation is explored using two neuroimaging techniques EEG and MRI while eye movements are recorded. Three experiments are performed: in MR scanner 1) functional localisation of specific areas: LOC, FFA, MT/V5, V1 and V2 and 2) a saccadic choice experiment; with EEG, replication of the experiments performed in the MR scanner and 3) an additional experiment of movement detection during the ocular saccades. Thirty young volunteers (18-40 y old) are involved.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Normal vision or corrected to normal
- •Social security affiliation
- •Signed consent to participate
- •No pregnancy fo women
Exclusion Criteria
- •Audition and motor troubles
- •Incapable to decide (Persons mentioned in L1121-5,6 et 8 of public health code)
- •Neurological disorders
- •Pathology affecting oculomotor control
- •MRI incompatibility
Outcomes
Primary Outcomes
Eye movement brain networks
Time Frame: 24 months
Identification of the cerebral locus of ocular movement via MRI \& EEG
Secondary Outcomes
- OculoDB(24 months)