Development of endoscopic Optical Coherence Tomography for Laryngeal cancer screening
Not Applicable
Completed
- Conditions
- aryngeal cancer screeningCancerMalignant neoplasm of larynx
- Registration Number
- ISRCTN32637181
- Lead Sponsor
- orth West London Hospitals NHS Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. All patients over the age of 18 years (no upper age limit)
2. Male or female gender
3. Patients able to provide informed consent to OCT-adapted flexible nasendoscope examination under topical local anaesthesia and completing a patient experience questionnaire provided at the end of procedure
4. Smokers and non-smokers
Exclusion Criteria
1. All patients under the age of 18 years
2. All patients from whom informed consent has not been obtained prior to tissue resection or OCT-adapted flexible nasendoscopy respectively
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Characterisation & correlation of mucosal pathology (OCT images vs Histopathology) following direct microlaryngoscopy and biopsy of laryngeal lesion under general anaesthesia (GA)
- Secondary Outcome Measures
Name Time Method Patient Experience Questionnaire at initial out-patient visit , immediately following nasendoscopy examination and image capture under LA