Newborn Feeding and Infant Phenotype

Imperial College London1 site in 1 country124 target enrollmentMarch 2010

ConditionsBreast Feeding

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Breast Feeding
Sponsor: Imperial College London
Enrollment: 124
Locations: 1
Primary Endpoint: Change in Total Adipose Tissue Volume
Status: Completed
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism.

I will compare adipose tissue and liver fat deposition in healthy, full term breast and formula fed infants babies shortly after birth and around 12 weeks.

Registry

clinicaltrials.gov

Start Date

March 2010

End Date

July 2012

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Imperial College London

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Healthy baby
•Term baby
•Appropriate weight for gestational age (UK - WHO 2009 growth charts)

Exclusion Criteria

•Infants of diabetic mothers
•Infants of smokers
•Infants fed non-commercial or non-cows milk based infant formulae

Outcomes

Primary Outcomes

Change in Total Adipose Tissue Volume

Time Frame: Between birth and 6-12 weeks age

Difference in total adipose tissue volume, measured using whole body magnetic resonance imaging.

Secondary Outcomes

Change in Regional Adipose Tissue Distribution Compared to Breastfed Infants.(Between birth and 6-12 weeks age)
Change in Intrahepatocellular Lipid Compared to Breastfed Infants.(Between birth and 6-12 weeks age)