Effect of Early Feeding of Breast Milk Versus Formula Milk on Health Status of Preterm
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 主要终点
- Number of participants with complete blood pictures
研究概览
简要总结
Breast milk is an extremely complex and highly variable biofliud that has evolved to nourish infants and protect them from disease whilst their own immune system matures. The composition of human breast milk changes in response to many factors, matching the infants requirement according to its age and other characteristics.
详细描述
Breast milk is an extremely complex and highly variable biofliud that has evolved to nourish infants and protect them from disease whilst their own immune system matures. The composition of human breast milk changes in response to many factors, matching the infants requirement according to its age and other characteristics.
Therefore, the composition of breast milk is widely believed to be specifically tailored by each mother to precisely reflect the requirements of her infant.
Human milk is uniquely suited to the human infant, both in its nutritional composition and in the non-nutritive bioactive factors that promote survival and healthy development.
Breast milk contains over 400 different proteins which perform a variety of functions; providing nutrition, possessing antimicrobial and immunomodulatory activities, as well as stimulating the absorption of nutrients.
The immune system of preterm infants is immature, placing them at increased risk for serious immune-related complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 1 Week 至 1 Month（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Gestational age <37 weeks.
- •Birth weight >1000 gm.
排除标准
- •Gestational age 37 weeks.
- •Birth weight < 1000 gm.
- •Newborns with congenital anomalies.
- •Newborns with suspected metabolic diseases.
- •Newborns on mechanical ventilators.
- •Newborns with suspected neonatal sepsis.
研究组 & 干预措施
preterm formula milk neoborn
will be given preterm formula milk
干预措施: preterm formula milk (Other)
exclusive breast milk
will be given exclusive breast milk
干预措施: exclusive breast milk (Other)
结局指标
主要结局
Number of participants with complete blood pictures
时间窗: 1 year
All newborn are examine
Weight gain
时间窗: 1 year
All newborn well examine regards weight 1. Necrotizing enterocolitis. 2. Neonatal Sepsis. 3. Weight gain. 4. Feeding tolerance
次要结局
未报告次要终点