Effects of Blueberry Consumption on Cardiometabolic Parameters in Men With Type 2 Diabetes.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Type2 Diabetes
- Sponsor
- Albany Research Institute, Inc.
- Enrollment
- 55
- Locations
- 1
- Primary Endpoint
- Blood Pressure
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Lifestyle strategies that include dietary modification, such as consumption of a plant-based diet, are well recognized in disease prevention and may improve type 2 diabetes. Various components of a plant-based diet may contribute to its beneficial health effects, but there has been keen interest in the possibility that plant polyphenols may have a role. Blueberries are dietary sources of polyphenols, specifically anthocyanins. To date there are few human clinical trials evaluating the beneficial health effects of blueberries in populations with type 2 diabetes. The objective of the study is to determine if freeze-dried blueberries compared to a blueberry placebo will improve cardiometabolic parameters in men with type 2 diabetes.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Ages 45 to 75 years at beginning of study
- •BMI \>25 kg/m2
- •HbA1C \> 6.5 and \< 9
- •Medical diagnosis of type 2 diabetes for at least 6 months
Exclusion Criteria
- •Use of insulin
- •Presence of chronic kidney disease (GFR \< 45 mL/min), liver cirrhosis, gastrointestinal disease, pancreatic disease, or malabsorption syndromes
- •Weight loss of \>10% of body weight over the last 6 months; routine participation in heavy exercise
- •Heavy smokers (\>20 cigarettes per day)
- •Unable or unwilling to give informed consent or communicate with study staff
- •Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigators may interfere with study participation or the ability to follow the intervention protocol
- •Allergies to blueberries or blueberry products
Outcomes
Primary Outcomes
Blood Pressure
Time Frame: 8 weeks
Systolic blood pressure and diastolic blood pressure.
Secondary Outcomes
- Hemoglobin A1C(8 weeks)