A Randomized, Double-Blind, split-mouth, Placebo-controlled, clinical trial of the effect of sub-gingival irrigation with ibuprofen mouthwash in treatment of periodontal Diseases
Phase 2
- Conditions
- Periodontal disesaes.Periodontal disesaes
- Registration Number
- IRCT2014050917587N4
- Lead Sponsor
- Deputy of Research Council Of Dental Branch, Islamic Azad University of Tehran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
Inclusion Criteria:
The patients systemically healthy were selected for the study. The subjects had with periodontal pocket depths of more than 4 mm on at least two teeth in mandibular molar area that observed on probing.
Exclusion Criteria
Existing systemic disease; Hypersensitive to Ibuprofen; The use of any Antibiotic or Anti-inflammatory drugs within the 6 months preceding the beginning of the study; Cancer; Pregnant or nursing females; Smoking; Orthodontic treatments; Extensive dental restorations; Use removal denture; Mouth rinses; during the entire period of the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pocket depth. Timepoint: 15 Days. Method of measurement: Periodontal pobe.;Clinical attachment level. Timepoint: 15 Days. Method of measurement: Periodontal probe.
- Secondary Outcome Measures
Name Time Method Reduction of bleeding on probing. Timepoint: 3 Months. Method of measurement: Periodontal probe.;Reduction of Plaque Index. Timepoint: 3 Months. Method of measurement: Loe & Silness Index.