Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease
- Conditions
- Ischemic Stroke
- Interventions
- Genetic: DNA sequencing
- Registration Number
- NCT02720861
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
To explore the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease in Thai patients.
- Detailed Description
This is an cross-sectional observational study in Chulalongkorn hospital, to determine the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease. Patients who are potentially eligible for study participation will be identified through a chart review of patients who were admitted in Chulalongkorn Hospital for acute ischemic stroke treatment.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Nationality in Thailand
- Age equal or more than 18 years
- Clinical and imaging diagnosis of acute ischemic stroke
- Patient consent to participate in the research
Exclusion Criteria
- High risk for cardioembolic stroke by TOAST classification
- Contraindication for venipuncture
- Pregnancy or breast feeding patient
- History of head and neck radiation
- Down's syndrome
- Marfan syndrome
- Autoimmune disease such as SLE
- Ongoing malignancy or remission of malignancy less than 1year
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description non embolic ischemic stroke DNA sequencing acute ischemic stroke from atherosclerosis or lacunar stroke
- Primary Outcome Measures
Name Time Method Number of Participants With RNF213 rs112735431 Gene polymorphism 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Suporn Travanichakul
🇹ðŸ‡Bangkok, Thailand