Randomized parallel controlled trial of "on demand" therapy versus continuous therapy of omepral 20mg in effectiveness and safety for the patients {Los Angeles classification grade M (LA M) or more)} diagnosed as the gastroesophageal reflux disease.
Not Applicable
- Conditions
- Gastroesophageal reflux disease (LA gradeM or more)
- Registration Number
- JPRN-UMIN000001937
- Lead Sponsor
- Department of Gastroenterology Juntendo University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients who suffer from cancer. 2) Patients who suffer from serious liver disease, kidney disease, heart disease, or Haematological disorder 3) Patients who had the past of irritability for omeprazole 4) Pregnant women and patienst while suckling, and patients who have been hoping for pregnancy for the trial period. 5) Patients who participated in other clinical trials which are thought to influence to the result of this trial within one month before the start of the trial. 6) Patients who refuse endoscopic examination. 7) Patients who suffer from gastric ulcers and/or duodenal ulcers 8) Patients who are judged inappropriate for the clinical trial by doctors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of change of GOS score between before and after treatment Amount of change of QULRAS-J score between before and after treatment
- Secondary Outcome Measures
Name Time Method Examination according to symptoms Evaluation of safety