Preventing oxygen desaturation during bronchoscopy in patients with COPD comparing two oxygenation methods

Not Applicable

Completed

• Conditions: Bronchoscopy in COPD patients; Respiratory

• Registration Number: ISRCTN18159882
• Lead Sponsor: niversity Hospital of Basel

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-02-17
• Study Completion: 2023-12-31
• Last Update Posted: 8 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 605

Inclusion Criteria

1. Age =18 years
2. Informed Consent as documented signature
3. Clinical indication for bronchoscopy
4. Prior diagnosis of COPD according to the GOLD criteria

Exclusion Criteria

1. Patients intubated at screening time
2. Bronchoscopy via tracheostomy tube
3. Patients requiring intubation for procedure
4. Prior enrolment in an intervention study within the last 30 days
5. Inability or contraindications to undergo the investigated intervention (i.e. active nasal bleeding; recent nasal surgery; base of skull defect or fracture)
6. Patients with oxygen saturation below 88% while breathing room air
7. Patient with hypercapnic respiratory failure (pCO2 > 6.5kPa) or other indications for non-invasive ventilation for bronchoscopy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cumulative hypoxemia time, defined as oxygen saturation <90%, during sedation for bronchoscopy measured using pulse oximetry