Optimization of exposure therapy by enhancing inhibitory learningmechanisms – Investigation of spider-phobic non-responders to virtual reality exposure therapy

Not Applicable

• Conditions: F40.2; Specific (isolated) phobias

• Registration Number: DRKS00022379
• Lead Sponsor: IMF Medizinische Fakultät

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-10
• Study Completion: 2022-11-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 134

Inclusion Criteria

Responder or Non-responder: Participant in the study of the CRC TRR58 Fear, anxiety and anxiety disorders

HC: indidivual without any psychiatric disorder current or lifetime

Exclusion Criteria

For healthy control, any current or life-time psychiatric disorder is an exclusion criterion.
Further exclusion criteria for all participants are medication, any neurological abnormalities,
organic mental disorders, dementia, brain injuries, or MRI contraindications.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30% reduction of the score in the Spider Phobia Questionnaire (pre-post)

Secondary Outcome Measures

Name	Time	Method
a final distance reduction of 50% in the Behavioral avoidance test (pre-post)