DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
Not Applicable
Active, not recruiting
- Conditions
- ST Segment Elevation Myocardial Infarction
- Registration Number
- NCT01435408
- Lead Sponsor
- Rigshospitalet, Denmark
- Brief Summary
This study focuses on Cardioprotective strategies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
- Age ≥ 18 years.
- Acute onset of chest pain of < 12 hours' duration.
- ST-segment elevation ≥ 0.1 mV in ≥ 2 contiguous leads, signs of a true posterior infarction or documented newly developed left bundle branch block.
Culprit lesion in a major native vessel.
Exclusion Criteria
- Pregnancy.
- Known intolerance of ASA, clopidogrel, heparin or contrast.
- Inability to understand information or to provide informed consent.
- Haemorrhagic diathesis or known coagulopathy.
- Stent thrombosis.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method All cause mortality, heart failure (postconditioning) 2 years
- Secondary Outcome Measures
Name Time Method All cause mortality, myocardial infarction, repeat revascularisation and occurrence of definite stent thrombosis according to ARC definition within 1 year (deferred stent strategy) 1 year Infarct size in relation to area at risk as determined by MRI after 3 month 3 month Infarct size Salvage index
Trial Locations
- Locations (5)
Department of Cardiology, Aalborg University Hospital
🇩🇰Aalborg, Denmark
Department of Cardiology, Skejby University Hospital
🇩🇰Aarhus, Denmark
The Heart Center, Rigshospitalet, University of Copenhagen
🇩🇰Copenhagen, Denmark
Department of Cardiology, Gentofte University Hospital
🇩🇰Hellerup, Denmark
Department of Cardiology, Odense University Hospital
🇩🇰Odense, Denmark
Department of Cardiology, Aalborg University Hospital🇩🇰Aalborg, Denmark