ISRCTN11596292进行中（未招募）未知
Intramuscular and Inflammatory Response to Acute Exercise in Chronic Disease (I-RACE)
niversity Hospitals of Leicester NHS Trust0 个研究点目标入组 65 人开始时间: 2017年11月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 65
研究概览
简要总结
2021 observational results in https://pubmed.ncbi.nlm.nih.gov/33888089/ (added 26/04/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Patient inclusion criteria:
- •Diagnosed CKD patients (eGFR<60ml/min/1.73m2). Renal transplant recipients (RTRs) will also be eligible.
- •Healthy control inclusion criteria:
- •Individuals with not diagnosed kidney disease (eGFR>80ml/min/1.73m2).
- •All participants must be willing and able to give informed consent for participation in the study.
排除标准
- •Patient exclusion criteria:
- •1. Age <18 years
- •2. Female participants who are pregnant, lactating, or planning pregnancy during the course of the study
- •3. Scheduled elective surgery or other procedures requiring general anaesthesia during the study
- •4. Any other significant disease or disorder (i.e. significant co-morbidity including unstable hypertension, potentially lethal arrhythmia, myocardial infarction within 6 months, unstable angina, active liver disease, uncontrolled diabetes mellitus (HbA1c =9%), advanced cerebral or peripheral vascular disease) which, in the opinion of the patient’s own clinician, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study
- •5. Inability to give informed consent or comply with testing and training protocol for any reason
- •6. Individuals who are currently, or have in the past 6 months, used immunosuppressive or anti-inflammatory medication other than that required by renal transplant recipients (RTRs) to prevent graft rejection
- •Healthy control exclusion criteria:
- •1. Age <18 years
- •2. Female participants who are pregnant, lactating, or planning pregnancy during the course of the study
- •3. Scheduled elective surgery or other procedures requiring general anaesthesia during the study
- •4. Chronic Kidney Disease (eGFR<80mL/min/1.73m2)
- •5. Any other significant disease or disorder (i.e. significant co-morbidity including unstable hypertension, potentially lethal arrhythmia, myocardial infarction within 6 months, unstable angina, active liver disease, uncontrolled diabetes mellitus (HbA1c =9%), advanced cerebral or peripheral vascular disease)
- •6. Individuals who are currently, or have in the past 6 months, used immunosuppressive medication
- •7. Inability to give informed consent for any reason
研究者
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