Effect of vitamin D3 on glycemic control, inflammatory markers and 24hr urine protein in patients with insufficiency and deficiency in serum vitamin D level in type 2 diabetes mellitus

Phase 3

Completed

• Conditions: Type 2 diabetes.; Non-insulin-dependent diabetes mellitus; E10, E11,

• Registration Number: IRCT2015081723656N1
• Lead Sponsor: Shahrekord University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2018-02-22

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients with type 2 diabetes treated with insulin or medication to lower blood sugar levels; have a vitamin D deficiency; insulin and blood sugar-lowering drugs are used on a regular basis; during the last month are not taking calcium and vitamin D supplementation; proteinuria more than 200 mg per 24 hours urine; the serum creatinine less than 2 or GFR above 50. Exclusion criteria: type 1 diabetes; the normal level of vitamin D; not cooperating with the regular use of drugs; serum creatinine greater than 2 or GFR less than 50; D Calcium intake during the last month; unwillingness to continue to participate in the study; calcium in phosphorus above 55; calcium greater than 10, all conditions that affect the ESR, except for the lack of vitamin D.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
FBS. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;Hemoglubin A1c. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;ESR. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;CRP. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;Proteinuria. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.

Secondary Outcome Measures

Name	Time	Method
Phosphor. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;Calcium. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.;Albumin. Timepoint: Before , two and four months after the intervention. Method of measurement: Lab data.