Effects of New Protein Bar on Biochemical and Physiological Parameters in Physically Active People
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Fat mass
研究概览
简要总结
Post-exercise nutrition is an important factor in a nutrition plan for physically active subjects. Focusing on that, the Serbian group is developing protein bars enriched with sports supplements. Slovenian partner group will investigate the effect of new protein bar consumption on body composition, biochemical parameters, and muscle regeneration after training. The new bar will be compared with a commercially available bar.
详细描述
The clinical study will be performed on 10 elite handball players from Slovenia handball club. It will be designed as a crossover study. Half of the participants will consume the new bar for five days and the other half will consume the control bar. After the five-day washout period, the groups will consume the bar which was not consumed in the first period.
At baseline, at the end of every intervention and washout period, the blood samples will be withdrawn, and the body composition will be analyzed.
The analyzed biochemical parameters will be basic serum parameters, such as fasting glucose, total cholesterol, LDL, HDL, triglycerides, aspartate aminotransferase (AST), alanine aminotransferase (ALT), C-reactive protein (CRP), and parameters related to the muscle regeneration and inflammation, such as creatine kinase, lactate dehydrogenase, insulin-like growth factor (IGF), tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), monocyte chemoattractant protein 1 (MCP-1).
In the second part of the study, the acute effect of consuming each bar after training will be tested. Each participant will consume both bars on separate days. The mentioned parameters will be assessed after training and immediately and 3h after bar consumption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •daily high-intensity physical activity
排除标准
- •smoking, cardiovascular, neurological, skeletal muscle disease, allergies
结局指标
主要结局
Fat mass
时间窗: 15 days
Fat mass in kilograms will be determined using bioelectrical impedance analysis (BIA).
Muscle mass
时间窗: 15 days
Muscle mass in kilograms will be determined using bioelectrical impedance analysis (BIA).
次要结局
- C-reactive protein(15 days)
- Lactate dehydrogenase(15 days)
- Tumor necrosis factor alpha(15 days)
- Creatine kinase(15 days)
研究者
Zala Jenko Praznikar
assistant professor
University of Primorska