Longterm Follow-up After Remote Ischemic Preconditioning for Prevention of Contrast-induced Nephropathy

• Conditions: Impaired Renal Function
• Interventions: Other: Ischemic preconditioning

• Registration Number: NCT01760031
• Lead Sponsor: University of Cologne

Brief Summary

Remote ischemic preconditioning reduces the incidence of contrast-induced acute kidney injury in patients undergoing elective coronary angiography. This study was designed to acquire long-term data of initially randomized patients in the RenPro Trial.

Detailed Description

Data of the RenPro Trial has been already published. In the present study data of longterm follow up are collected.

Study Timeline

• Study Start: 2012-07
• Status Verified: 2012-12
• Primary Completion: 2012-12
• Study First Submitted: 2012-12-28
• Study First Submitted QC: 2012-12-28
• Last Update Submitted: 2012-12-28
• Study Completion: 2013-01
• Study First Posted: 2013-01-03
• Last Update Posted: 2013-01-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 81

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Subjects with impaired renal function	Ischemic preconditioning	Subjects with baseline impaired renal function undergoing cardiac catheterization with contrast-medium exposure

Primary Outcome Measures

Name	Time	Method
MACCE	1 Year	Major Adverse Cardiac and Cerebrovascular Events (Combined primary endpoint): All-cause mortality, cardiovascular mortality, rehospitalization, stroke, myocardial infarction, hemodialysis

Secondary Outcome Measures

Name	Time	Method
Renal function	1 year	changes of serum creatinine, eGFR, NGAL and cystatin C compared to baseline in both groups.

Trial Locations

Locations (1)

University of Cologne; 🇩🇪 Cologne, NRW, Germany