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临床试验/NCT01023152
NCT01023152已完成不适用

Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass

Yonsei University0 个研究点目标入组 74 人开始时间: 2009年12月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
74

研究概览

简要总结

The purpose of this study is to study the effect of remote ischemic preconditioning on acute kidney injury in patients undergoing heart valve replacement surgery with cardiopulmonary bypass.

详细描述

Hypothesis

RIPC using tourniquet might be a simple technique with the benefit to provide renal protection without disturbing operating procedure and prolongation of total operating time.

研究设计

研究类型
Interventional
干预模型
Parallel
主要目的
Prevention

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients undergoing complex valve surgery.

排除标准

  • older than 80 years
  • those with left main disease >50%, or hepatic or pulmonary disease
  • active infective endocarditis
  • left ventricular ejection fraction <30%
  • myocardial infarction (MI) within 3 weeks
  • pre-existing renal dysfunction (serum creatinine (Cr) level >1.4 mg/dl), and those with peripheral vascular disease affecting the lower limbs.

研究者

申办方类型
Other

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