Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass

Yonsei University0 sites74 target enrollmentDecember 2, 2009

ConditionsHeart Valve Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Valve Disease
Sponsor: Yonsei University
Enrollment: 74
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The purpose of this study is to study the effect of remote ischemic preconditioning on acute kidney injury in patients undergoing heart valve replacement surgery with cardiopulmonary bypass.

Detailed Description

Hypothesis : RIPC using tourniquet might be a simple technique with the benefit to provide renal protection without disturbing operating procedure and prolongation of total operating time.

Registry

clinicaltrials.gov

Start Date

December 2, 2009

End Date

TBD

Last Updated

16 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Yonsei University

Eligibility Criteria

Inclusion Criteria

•patients undergoing complex valve surgery.

Exclusion Criteria

•older than 80 years
•those with left main disease \>50%, or hepatic or pulmonary disease
•active infective endocarditis
•left ventricular ejection fraction \<30%
•myocardial infarction (MI) within 3 weeks
•pre-existing renal dysfunction (serum creatinine (Cr) level \>1.4 mg/dl), and those with peripheral vascular disease affecting the lower limbs.