High-field MRI of the compression of the anterior visual pathway in pituitary adenoma

Completed

• Conditions: macroadenoma; Pituitary tumour; 10021112; 10015917; 10019190

• Registration Number: NL-OMON45804
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 4

Inclusion Criteria

Patients diagnosed with a pituitary macro adenoma

Exclusion Criteria

1. Age <18 years or >70 years
2. Renal failure or previous allergic reactions to contrast agent
3. Known pathology that could simultaneously effect visual fields e.g. glaucoma
4. Contraindications to MRI scanning, including:
a. Claustrophobia
b. Pregnancy
c. Pacemaker and defibrillator
d. Nerve stimulators
e. Intracranial clips
f. Metallic fragments
g. Ferromagnetic implants
h. Hydrocephalus pump
i. Permanent make-up
j. Tattoos situated above the shoulder region
k. Piercings that cannot be removed
l. Subjects who are unable to lie still e.g. due to Tremor, Parkinson*s disease
m. Severe physical disability (completely wheelchair bound)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Radiological descprition of the optic-chiasmatic system, this will lead to the<br /><br>evaulation of:<br /><br>-The configuration of the anterior optic pathway/optic chiasm<br /><br><br /><br>Ophthalmic description:<br /><br>-Thickness of the optic-nerve fibre layer on OCT<br /><br>-Visual field defect noted on Humphrey analyser<br /><br>-Visual acuity through EDTRS-chart<br /><br>-Visual functioning questionnaire </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable </p><br>