Oral Rehydration Solution Orange vs. Apple/Blackcurrant in addition to standard bowel preparation in colonoscopy: a Pilot Study

Not Applicable

• Conditions: Bowel preparation pre-colonoscopy; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12613000917730
• Lead Sponsor: Assoc/Prof Gregor Brown

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-08-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Consenting adult patients (aged >18 years) undergoing outpatient colonoscopy for clinically accepted indications. Clinically accepted indications for colonoscopy generally include but are not restricted to; iron deficiency anaemia, surveillance of bowel polyps, colorectal cancer screening, assessment of symptoms such as abdominal pain, diarrhoea and constipation, assessment or investigation of inflammatory bowel disease.

Exclusion Criteria

Exclusion criteria are conditions generally considered as exclusions to colonoscopy in normal clinical practice. They are suspected bowel perforation, gastric outlet obstruction, toxic megacolon, severe colitis, and pregnancy or lactation. For additional safety, will also exclude patients with the relative contraindications of renal impairment (eGFR<60) and heart failure (New York Heart Association Class III or IV). Prep-Kit C is contraindicated in individuals with phenylketonuria, due to the presence of aspartame and patients with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency given it contains ascorbic acid (vitamin C) which is an oxidant. Diabetics will also be excluded due to the high level of dextrose in OHS. Any person with a known hypersensitivity to a constituent of Picoprep, Glycoprep or OHS will also be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of correct estimations of colour of oral hydration solution consumed before colonoscopy will be the primary endpoint. This will inform future studies and suitability of use of these products pre-procedure.<br><br>The endoscopist will be asked to assess the acceptability of the bowel preparation at completion of the colonoscopy on the day of procedure. They will rate the bowel preparation using the Ottawa Scale, and will complete a datasheet where they will be asked to estimate which colour fluid the patient ingest pre-procedure.[Day of procedure]