NL-OMON53883尚未招募不适用
Timing exercise training as strategy to improve insulin sensitivity and substrate metabolism in men and woman with pre-diabetes - Timed Training Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Participants are able to provide signed and dated written informed consent
- •prior to any study specific procedures
- •Aged 40-75 years
- •Body mass index (BMI) >=25 kg/m2
- •Male, or postmenopausal (at least 1 year post cessation of menses) female
- •Have suitable veins for cannulation or repeated venepuncture
- •Pre-diabetes based on one or a combination of the following criteria:
- •o Impaired Glucose Tolerance (IGT): plasma glucose values >= 7.8 mmol/l and <=
- •11.1 mmol/l 120 minutes after glucose drink consumption during OGTT in screening
- •o Impaired Fasting Glucose (IFG): Fasting plasma glucose >= 6.1 mmol/l and <= 6.9
- •o Insulin Resistance: glucose clearance rate <= 360 mL/kg/min, as determined
- •during the OGTT using OGIS120
- •o HbA1c of 5.7-6.4%
排除标准
- •Type 2 diabetes
- •Patients with active congestive heart failure and and/or severe renal and or
- •liver insufficiency
- •Uncontrolled hypertension
- •Any contra-indication for MRI scanning
- •Alcohol consumption of >3 servings per day for man and >2 serving per day for
- •Unstable body weight (weight gain or loss > 5kg in the last 3 months)
- •Previous enrolment in a clinical study with an investigational product during
- •the last 3 months or as judged by the Investigator which would possibly hamper
- •our study results
- •Medication use known to hamper subject*s safety during the study procedures
- •Subjects who do not want to be informed about unexpected medical findings
- •Men: Hb <8.0 mmol/L, Women: Hb <7.0 mmol/l
- •Heavily varying sleep-wake rhythm (i.e. night shift work and travels across
- •time zones).
- •Significant food allergies/intolerance (seriously hampering study meals)
- •Blood donation during or within 2 months prior to the study
研究者
相似试验
已完成
不适用
Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetesPre-diabetesOverweight and ObesityNCT06014684Maastricht University Medical Center15
已完成
不适用
Optimal Timing of a tailored Physical Activity program during chemotherapeutic Cancer Treatment to reduce long-term cardiovascular morbidity.cardiovasculaire aandoeningencardiovascular effect after chemotherapy1000054610027656NL-OMON47553niversitair Medisch Centrum Groningen275
已完成
不适用
Development of an exercise program to improve the drinking effect of fortified milk: focusing on the muscle mass and muscle strength in older adultsDecrease muscle mass and decline muscle strengthJPRN-UMIN000018972niversity of Tsukuba60
招募中
2 期
Determine effective training program for improving relationship between patient and assistantIRCT2017102228342N2Vice chancellor for research, Iran University of Medical Sciences64
已完成
3 期
Development of exercise training regimen as second prevention for breast cancer survivors.postmenopausal women with breast cancerJPRN-UMIN000013475Hamamatsu university school of medicine94