Optimal Timing of a tailored Physical Activity program during chemotherapeutic Cancer Treatment to reduce long-term cardiovascular morbidity. - ACT trial

niversitair Medisch Centrum Groningen0 个研究点目标入组 275 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•- Patients with testicular, early colon, early breast cancer or B-cell non-Hodgkin lymphoma (B-NHL) with an indication for systemic chemotherapy with a curative intent
•- Normal blood count at start of systemic treatment
•- Patients need to have an adequate physical health, which is defined by diastolic blood pressure >45 mm Hg or <95 mm Hg; heart frequency in at rest < 100 per minute; body temperature below 38°C; respiration frequency in rest below 20 per minute
•- Written informed consent
•- Adequate cardiac function with a LVEF above the lower limit of normal

•- infections requiring actual antibiotics
•- signs of ongoing bleeding or fresh petechiae; unexplained bruises
•- critical organ impairment due to their malignancy
•- not recovered from earlier surgical intervention
•- non adequate control of any symptoms of the malignancy
•- inability to travel independently to the rehabilitation centre
•- cognitive disorder or emotional instability that might impede the participation in the training program
•- recent cardiovascular event

发起方