Examining the longitudinal associations between negative peer experiences on adolescent inflammatio

Completed

• Conditions: Heightened inflammation; Not applicable; 10001474

• Registration Number: NL-OMON46973
• Lead Sponsor: niversiteit van Tilburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

Adolescents enrolled in the first year of high school.

Exclusion Criteria

Autoimmune diseases and/or hyperactive thyroid

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>High sensitivity C-reactive protein (hsCRP), an index of systemic inflammation,<br /><br>will be assessed at each wave of data collection using dried blood spots. The<br /><br>main study parameter is changes in hsCRP over time as a function of exposure to<br /><br>negative peer experiences (e.g., peer victimization, peer rejection) across<br /><br>adolescents with different levels of interpersonal sensitivity. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>This project also offers the opportunity to address a number of relevant<br /><br>secondary objectives, concerning a) the link between inflammation and<br /><br>depression, b) developmental transactional effects across peer adversity,<br /><br>inflammation and internalizing symptoms and c) the relationship between<br /><br>self-conscious emotion and inflammation. Therefore, this study will include<br /><br>internalizing symptoms (i.e., depressive symptoms, anxiety, loneliness),<br /><br>self-conscious emotion and emotion regulation as secondary parameters. </p><br>