Evaluation of association between presence of Chromosomal Aberrations in different patterns of Orofacial Clefts.
Not Applicable
- Conditions
- Health Condition 1: Q35-Q37- Cleft lip and cleft palate
- Registration Number
- CTRI/2019/11/021945
- Lead Sponsor
- Department of Oral and Maxillofacial surgery MGM dental college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
participants with uni or bilateral, complete or incomplete cleft lip/ palate
participants with sub mucous clefts
participants with any tessier soft tissue or bony clefts
participants with any combination of above clefts
participants who may or maynot have been operated previously for the above conditions
participants with orofacial clefts with or without systemic co morbidities
participants with orofacial clefts with or without other congenital deformities
prediagnosed syndromic patients with orofacial clefts
Exclusion Criteria
participants with features other than orofacial clefts
participants not willing to participate in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical features of Orofacial Clefts will be recorded. A thorough Systemic examination will be done to note the other systems if any involved with anomalies. Karyotyping will be done using the blood samples of the participants included in the study and a correlation will be done between the Phenotypic features and the chromosomal Aberrations if any.Timepoint: Day 1
- Secondary Outcome Measures
Name Time Method To correlate the Incidence of Orofacial Clefts with the Maternal history.Timepoint: Day 1;To determine the Incidence of Chromosomal Aberrations in Orofacial cleft patients. <br/ ><br>Timepoint: Day 1