Evaluation of different treatment thresholds in a clinical pathway for children with acute asthma

Recruiting

• Conditions: acute asthma; asthma exacerbation; 10006436

• Registration Number: NL-OMON50952
• Lead Sponsor: Martini Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 130

Inclusion Criteria

-children 2-18 years of age admitted for acute asthma
-treatment for acute asthma according to current dutch guideline
-supplemental oxygen use, low flow or high flow

Exclusion Criteria

-severe acute asthma for which intravenous albuterol is indicated
-unstable heart disease
-cystic fbrosis or other chronich or congenital lung disease
-any neurological disease
-any muscular disease
-developmental delay

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome is the difference in admission time for children with acute<br /><br>asthma who are treated according to the current nurse-driven pathway or the new<br /><br>pathway with adjusted treatment thresholds for patients who need supplemental<br /><br>oxygen. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are<br />-number of bronchodilator adminstrations per patient,<br />-the number of deviations from the pathway; administration of bronchodilators<br />when not indicated or when bronchodilators were indicated but not<br />administered.<br />-number or assessments by attending physician<br />-number of patients excluded because they needed treatment with intravenous<br />albuterol<br />-number of re-admission within one week<br />-association between heart rate and the total CAS en individual items of CAS<br />-difference between groups in administration of intravenous magensiumsulphate<br />-difference between groups in transfer to pediatric intensive care unit</p>