An assessment about impression of oral Methylnaltrexone on time of beginning of the bowel sounds after abdominal hysterectomy
- Conditions
- Postprocedural disorders of genitourinary system, not elsewhere classified.Postprocedural disorder of genitourinary system, unspecified
- Registration Number
- IRCT201104121946N8
- Lead Sponsor
- Vice Chancellor for research-Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 66
1) women who were 35-55 years old (with ASA class I&II) .2) without history of susceptible diseases for post-operative nausea and vomiting for example peptic ulcer, gastritis and uses of chemotherapy's drugs. 3) Lack of history about chronic constipation , IBS and IBD. 4) Without history of drug reaction to Naltrexone , another drugs, foods and seasonal allergies or asthma. 5) Lack of kidney's diseases.6) lack of liver's diseases especially hepatitis. 7) lack of addiction to opioids (Tramadol, Morphine, Percocet) and alcohol.8) lack of using psychological drugs/pain reliefer with Codeine or Propoxyphene/ Clonidine/ Disulfiram/ Laxative/ Immunosuppress drugs/ thyroglobulin for diagnose Hashimoto's thyroiditis or hypothyroidism.9) Without history for laparatomy twice or more than. 10) lack of lung's diseases. 11) Without history of organ's transplantation. Exclusion criteria: 1) duration of operation more than two hours.2) existence of another operation accompanied by hysterectomy.3) incidence of oparation's or anesthesia's side-effects.4) hypertension.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method An assessment about impression of oral Methylnaltrexone on time of beginning of the bowel sounds after abdominal hysterectomy. Timepoint: 12 hours after operation, every hour. Method of measurement: Patient visits, listening to bowel sounds.
- Secondary Outcome Measures
Name Time Method