Evaluation of clonidine as an adjuvant in spinal anaesthesia
Not Applicable
- Conditions
- Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium
- Registration Number
- CTRI/2021/02/031199
- Lead Sponsor
- Dr Aman Malawat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Pregnant women undergoing Elective lower segment Caesarean
section with ASA I and II grades.
2. Planned for elective lower segment caesarean section with a singleton
fetus & pregnancy at term
3. Patients with age between 18 years and 40 years
4. Patients with weight range between 40-80 kgs.
5. Patients with height between 150cm â?? 180 cm.
Exclusion Criteria
1. Parturients with maternal cardiac and haematological disease, diabetes, eclampsia, bleeding or coagulation test abnormalities, foetal distress and foetal anomalies.
2. Patients with known sensitivity to clonidine
3. Patients with compromised respiratory status like asthma, renal and
4. Hepatic disorders were excluded.
5. Patients on antihypertensive medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare perioperative haemodynamic changes.Timepoint: baseline
- Secondary Outcome Measures
Name Time Method compare the side effects of intrathecal hyperbaric bupivacaine and combination of hyperbaric bupivacaine with clonidineTimepoint: baseline;compare the time taken for rescue analgesia in two groups.Timepoint: baseline;To determine the onset of sensory/motor block and recovery from motor block with intrathecal hyperbaric bupivacaine and combination of hyperbaric bupivacaine with clonidine .Timepoint: baseline;To evaluate the safety of intrathecal hyperbaric bupivacaine and combination of hyperbaric bupivacaine with clonidine in terms of maternal and fetal outcome.Timepoint: baseline