Dietary supplementation with Omega in pregnant and the placentary vascular resistance assessed through the doppler of the uterine arteries
- Conditions
- hypertension and prenatal careC14.907.489E02.760.786
- Registration Number
- RBR-5kbzdh
- Lead Sponsor
- Faculdade de Medicina de Barbacena
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- Female
- Target Recruitment
- Not specified
Pregnant women enrolled in prenatal care of the institution.
Pregnant women who signed the free and informed consent form.
Pregnant women who attend the appointments (with even a missed prenatal) and agree to perform the protocol of the service, clinical examinations and imaging.
Pregnant women with hereditary or acquired thrombophilias identified
previously.
Pregnant women with identified risk factor for preeclampsia or CIUR selected from ACOG and NICE data adapted for this study:
i. Identification of two anamnesis clinical data (clinical history of PE in previous pregnancy, history
PE in first-degree relative, BMI> 35 kg / m2, hypertension, nephropathy, disease
autoimmune).
ii. Identification of anamnesis clinical data associated with changes in uterine artery doppler in the
first trimester (IR, PI or bilateral doppler notch).
iii. MAP identification> 100 in the first trimester of pregnancy associated with clinical history or Doppler
altered uterine artery (PI, IR, uterine artery notch).
Pregnant women - under 19 years.
Pregnant women who are absent from consultations - two or more consecutive prenatal absences.
Pregnant women who do not accept to use the omega in the prenatal or have intolerance to the use of the omega.
Smoking patients.
Gestantes without risk factor or thrombophilia.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of placental vascular resistance in association with omega - measured through the resistance index (RI) of the uterine artery through Doppler ultrasonography;Reduction of placental vascular resistance in association with omega - measured through the pulsatiity index (PI) of the uterine artery through Doppler ultrasonography
- Secondary Outcome Measures
Name Time Method Preeclampsia<br><br>Measured through the measurement of pregnant women 's blood pressure. Two evaluations at 4-hour intervals, with values ??equal to or greater than 140/90 mmHg + proteinuria at urinalysis of at least 300 mg / dl in 24-hour urine;Oligohydramnio<br><br>Evaluation of the volume of amniotic fluid identified through sonographic examination through the amniotic fluid index (ILA) described by Phelan et al.;Restricted intrauterine growth (RCIU)<br><br>Evaluation of fetal growth parameters identified by ultrasound examination. CIUR is considered when the fetus presents fetal growth below the 10th percentile for gestational age. Parameters: biparietal diameter, femur length and fetal abdominal circumference.