Gender specific responses in platelet function following long chain omega-3 fatty acid supplementatio
Phase 1
Recruiting
- Conditions
- Platelet aggregationBlood - Normal development and function of platelets and erythrocytesCardiovascular - Normal development and function of the cardiovascular system
- Registration Number
- ACTRN12609000164291
- Lead Sponsor
- The University of Newcastle
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Healthy participants aged 25 years or above.
Exclusion Criteria
Participants diagnosed with any hematological or cardiovascular disorders and are taking fish oil capsules or medication affecting coagulation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of this trial is to determine the gender-specific responses in platelet function (aggregation) following omega-3 fatty acid supplementation.[Blood samples from participants will be collected at the commencement of the study (prior to suppplementation) and again at 2, 5 and 24 hours following supplementation. Whole blood platelet aggregation, platelet count, biomarkers of coagulation and a complete plasma lipid profile will be generated from each blood sample.]
- Secondary Outcome Measures
Name Time Method The secondary outcome is to compare the efficacy of each individual long chain omega-3 fatty acid (Eicosapentaenoic Acid, Docosahexaenoic Acid) to inhibit platelet aggregation at each timepoint by analysis of blood samples.[All these outcomes will be measured at baseline, 2, 5 and 24 hours post intervention.]