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Venous Sinus Stenting for Idiopathic Intracranial Hypertension Refractory to Medical Therapy

Phase 1
Completed
Conditions
Idiopathic Intracranial Hypertension (IIH)
Interventions
Device: Venous Sinus Stenting
Registration Number
NCT01407809
Lead Sponsor
Weill Medical College of Cornell University
Brief Summary

Idiopathic Intracranial Hypertension (IIH) is a disease that affects mainly young people, and is associated with headache and loss of vision. The medical and surgical management of IIH is problematic and many patients are not treated effectively. Some cases of IIH are associated with severe stenosis of the large veins of the brain and various researchers have recently reported significant improvement in patients with IIH after the narrow veins of the brain were treated with a stent. Our project aims to evaluate the safety and long-term efficacy of venous sinus stenting in patients with severe IIH refractory to medical management.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
InterventionVenous Sinus Stenting-
Primary Outcome Measures
NameTimeMethod
Absence of procedure related and device related complications.24 months
Greater than 2 decibel (dB) mean deviation compared to the pre-operative field testing.24 months
Clinically significant cerebrospinal fluid (CSF) pressure reduction AND improvement of more than one grade in the Humphrey Field SITA Standard 24-2 Test grading scale.24 months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

New York Presbyterian/ Weill Cornell Medicine

🇺🇸

New York, New York, United States

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