A Controlled Randomized Trial Comparing Spinal Versus General Anesthesia for Transabdominal Preperitoneal (TAPP) Repair of Inguinal Hernia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Larissa University Hospital
- Enrollment
- 140
- Locations
- 1
- Primary Endpoint
- Postoperative opioid consumption
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of the study is to assess whether spinal anesthesia is superior to the standard general anesthesia or not for patients undergoing transabdominal preperitoneal inguinal hernia repair (TAPP).
Detailed Description
Anesthesia for laparoscopic procedures, including transabdominal preperitoneal inguinal hernia repair(TAPP) is synonymous with general anesthesia because of the adverse effects of the CO2 pneumoperitoneum on the awake patient, and regional anesthesia is preferred only in patients where general anesthesia is contraindicated. Α pilot study of our hospital has recently shown the feasibility to perform successfully and safely transabdominal preperitoneal inguinal hernia repair with low pressure CO2 pneumoperitoneum under spinal anesthesia.After this pilot study and based on previous experience in regional anesthesia for laparoscopic procedures, we designed a controlled randomized trial in order to compare spinal anesthesia with the standard general anesthesia for patients undergoing transabdominal preperitoneal inguinal hernia repair (TAPP).
Investigators
Chamaidi Sarakatsianou
RN,MSc
Larissa University Hospital
Eligibility Criteria
Inclusion Criteria
- •ASA physical status I-III
- •Normal coagulation profile
Exclusion Criteria
- •Non-reducible/obstructed hernias
- •Previous open surgery in the lower abdomen
- •Contraindication for pneumoperitoneum
- •Contraindication for spinal or/and general anesthesia
- •History of chronic pain or daily intake of analgesics
- •Psychiatric disorders
- •Inability of patients to use PCA pump
Outcomes
Primary Outcomes
Postoperative opioid consumption
Time Frame: Every 8 hours
The total dose of morphine was calculated as mg and administered by PCA pump
Secondary Outcomes
- Quality of life(6 months after the operation)
- Patient satisfaction(2 weeks after the operation)
- Complications(1 year)
- Postoperative pain(Every 8 hrs)
- Side- effects(Every 8 hrs)
- Hospital stay(Patients will be followed for the duration of hospital stay)
- Chronic Pain(12 months after the operation)