A Randomized Controlled Trial Comparing Postoperative Pain Following Total Abdominal Hysterectomy With General Anesthetic vs. Combined General and Spinal Anesthetic
Overview
- Phase
- Not Applicable
- Intervention
- General Anesthesia (control group)
- Conditions
- Hysterectomy
- Sponsor
- University of Saskatchewan
- Locations
- 1
- Primary Endpoint
- Total Morphine consumption
- Status
- Withdrawn
- Last Updated
- 9 years ago
Overview
Brief Summary
The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay following a total abdominal hysterectomy.
Investigators
Jacelyn Larson
Faculty
University of Saskatchewan
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiologists' (ASA) I and II patients undergoing elective Total Abdominal Hysterectomy at the Saskatoon City Hospital
- •Lower transverse abdominal incision
Exclusion Criteria
- •BMI \> 40
- •The TAH is treatment for cancer
- •A history of regular opioid use
- •Any medical condition that would make a spinal inadvisable,
- •An allergy or medical condition that would make it inadvisable to receive the drugs used in this study (eg. Peptic ulcer disease), or
- •If you will also be having a salpingo-oophorectomy).
Arms & Interventions
General Anesthesia
Intervention: General Anesthesia (control group)
General Anesthesia + Spinal Anesthesia
Intervention: General Anesthesia + Spinal anesthesia combined
Outcomes
Primary Outcomes
Total Morphine consumption
Time Frame: Post-operative day 2
The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.
Morphine consumption
Time Frame: 1 day
The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.
Secondary Outcomes
- Pain score on the VAS(On post-operative day 2 at 22:00)