NCT00685282已完成不适用
The Effect of Stress on DNA Integrity and the Effect of Cognitive Behavioral Therapy on Stress and Infertility in Women Undergoing IVF Treatment.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- pregnancy
研究概览
简要总结
The general hypothesis of the research is that stress decreases fertility and that Cognitive Behavioral Therapy will reduce stress and increase fertility. Secondarily, we hypothesize that stress has a detrimental effect on DNA integrity and that stress reduction will reduce DNA damage in the cell.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women between the ages of 18-35 without children undergoing IVF treatment
排除标准
- •undergoing treatment for a DSM-IV axis I psychiatric illness.
结局指标
主要结局
pregnancy
时间窗: two years
次要结局
- decreased stress(two months)
- DNA damage/ γH2AX(with in IVF cycle (2 months))
研究者
Eitan Lunenfeld
Head of the IVF Unit at the Soroka Medical Center
Soroka University Medical Center
研究点 (2)
Loading locations...
相似试验
终止
1 期
Brief Stresses Experimental StudyDNA DamagePsychological StressNCT03893617Dana Bovbjerg239
招募中
不适用
Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy SubjectsHealthyNCT06229002Hôpital le Vinatier40
已完成
不适用
eural correlates of stress-related gene-environment interactionsvulnerability for stress-related psychiatric disorders, such as depression, posttraumatic stress disorder, alcohol dependenceF32.9F43.1F10Depressive episode, unspecifiedMental and behavioural disorders due to use of alcoholPost-traumatic stress disorderDRKS00003604Zentralinstitut für Seelische Gesundheit,Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters309
Enrolling By Invitation
不适用
Intern Health StudyDepressionNCT01809080University of Michigan25,000
招募中
不适用
Evaluation of the Relationship Between Oxidative Stress and Human ReproductionPregnancyOxidative StressFertility DisordersIVFNCT05575739Calla IVF Center80