MedPath

To evaluate the effect of lumbar spine manipulation on sympathetic skin response and disability in chronic low back pain patients

Phase 2
Not yet recruiting
Conditions
Other disorders of the musculoskeletal system and connective tissue,
Registration Number
CTRI/2022/08/044938
Lead Sponsor
Sahil Kalra
Brief Summary

**ETHICAL STATEMENT**

Ethicalclearance will be received by the institutional Research Ethical Committee of Maharishi Markandeshwar (Deemed to be University)Mullana, Ambala, Haryana and will be done in accordance with Helsinkideclaration revised 2013 and National Ethical Guidelines for BiomedicalResearch involving Human Participants, 2017.

**Recruitment and intervention**

Mobilization/Manipulation is usedas an effective intervention in the management of patients with chronic lowback pain. Painand sympathetic activity have shown to be associated closely and it is ofutmost importance for physiotherapists to consider the impact of interventionon the sympathetic nervous system. Participants will receive two treatment sessions per week for consecutive 3 weeks. They will be assessed before and after the interventions and follow up after 3 weeks. There will be two treatment groups experimental group and the sham group. experimental group receive lumbar manipulations and conventional physiotherapy. Sham group receives only conventional therapy

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Both males and females of age 19-40 years 2 chronic mechanical low back pain from last 3 months 3.
  • Minimum score of 10 on Modified Oswestry Disability Index.
Exclusion Criteria
  • Neurological condition: Nerve compression and cauda equina syndrome 2.
  • Osteoporosis and osteopetrosis 3.
  • Aortic aneurysm and haemophillic joints 4.
  • All known mechanical conditions of low back pain 5.
  • Uncoperative patients 6.
  • Pregnancy 7.
  • Malignancy.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Galvanic skin response Biofeedbackbaseline and post treatment (immediate) follow up after last session of 3 week
Secondary Outcome Measures
NameTimeMethod
Modified Oswestry disability indexbaseline and post treatment (immediate) follow up after last session of 3 week

Trial Locations

Locations (1)

Musculoskeletal out patient department, Department of Musculoskeletal

🇮🇳

Ambala, HARYANA, India

Musculoskeletal out patient department, Department of Musculoskeletal
🇮🇳Ambala, HARYANA, India
Sahil Kalra
Principal investigator
7015426087
sahilkalrask01@gmail.com

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.