"Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 295
- 试验地点
- 2
- 主要终点
- HADS score
研究概览
简要总结
Chronic obstructive pulmonary disease (COPD) stands out among chronic diseases with its high and rising prevalence and mortality, poor quality of life, high re-hospitalization rates and societal burden of care. Current therapeutic and management practices are generally met with limited success. Research in recent years have highlighted the high level of psychiatric co-morbidity in COPD patients, and the major prognostic significance of anxiety/depression in COPD outcomes such as re-hospitalization, smoking cessation, quality of life, and survival. This suggests that addressing psychiatric and psycho-social aspects of care prominent in COPD patients may have strongly positive impact on outcomes, but the available evidence of effectiveness is limited.
The primary aim of the proposed research is to evaluate the effectiveness of a holistic disease management paradigm of psychiatric liaison consultation (CL) that integrates psychiatric and respiratory care to improve outcomes for COPD patients. This integrated psychiatric consultation liaison (IPCL) management paradigm includes the routine screening and structured collaborative care of anxiety and major depressive symptoms and depressive/anxiety disorder in COPD patients. We postulate that the IPCL care paradigm would reduce mood symptoms, increase smoking quit rates, reduce symptom burden and functional disability, and improve quality of life, while reducing rehospitalization, emergency department (ED) and unscheduled physician visits. A secondary aim is to evaluate its cost effectiveness by concurrently collecting resource utilization data.
详细描述
Specific Aims
The aim of the proposed research is to evaluate the effectiveness of a holistic disease management paradigm of) that integrates psychiatric and respiratory care (Integrated Psychiatric Consultation Liaison, IPCL) that addresses the high level of psychiatric co-morbidity in COPD patients to improve COPD outcomes.
Methods
Patient population Inpatients and specialist outpatients with established clinical diagnosis of chronic obstructive pulmonary disease (COPD).
Settings
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inpatients and specialist outpatients from: NUHS, SGH, CGH, SLH and AH.
- •Clinical diagnosis of chronic obstructive pulmonary disease (COPD) based on history, physical examination, spirometry, measurement of arterial blood gases, and chest radiographs, that meets the criteria for COPD as defined in the Global Initiative for Chronic Obstructive Lung Disease (GOLD).
- •COPD patients include cases of all grades of severity, and co-morbidity, without restriction.
- •Participants provide written informed consent.
排除标准
- •Known diagnosis of a psychiatric disorder that is under treatment.
- •Terminally ill COPD patients who are unable to complete baseline assessments.
研究组 & 干预措施
Usual control
Usual control will be provided with usual standard management of COPD and psychiatric comorbidities.
干预措施: Usual control (Procedure)
Integrated care
Integrated care will be provided with integrated care management.
干预措施: Integrated care (Procedure)
结局指标
主要结局
HADS score
时间窗: over 12 months
Anxiety and depression symptoms and diagnosis
次要结局
- Resource use and direct costs of care(over 12 months)
研究者
A/Prof Ng Tze Pin
Research Director
National University of Singapore
